Autonomic intelligence

We taught AI to read the nervous system — from heartbeats.

The autonomic nervous system runs every organ in constant coordination. Reading it used to take a clinic. Our AI reads it from a wearable you already own.

Input signalHeart rate
DomainFrequency
ResolvedTwo branches
HardwareA wearable you own
Fig. 01 — HRV frequency spectrumOur AI resolving the two autonomic branches from a heartbeat signal.
02The control layer

The body isn’t 100+ specialties. It’s one system.

Medicine reads the body in slices. But the body runs as one integrated system, coordinated by the autonomic nervous system — the control layer beneath heart, sleep, hormones, metabolism, immunity, and digestion, in constant coordination.

Fig. 02 — ANS ↔ organ coordination
ANS
CORE
Heart
Sleep
Hormones
Metabolism
Immunity
Digestion
Physiology only · no condition labels
03Signal

HRV, one layer deeper.

Heart-rate patterns carry more than a single number — but parts of the signal are ambiguous about which autonomic branch they come from. Resolving them is a hard signal-processing problem. Our model separates sympathetic and parasympathetic activity from heart-rate data — turning one of the most commoditized sensors there is into a window on the body’s control layer.

ParasympatheticRFa band
SympatheticLFa band
Method, in one line

A heartbeat trace goes in. Two branch-level activity signals come out — separated in the frequency domain, continuously, from a wearable’s data.

03AThe model · CAJAL

Meet CAJAL — the first AI model for the nervous system.

CAJAL is named for Santiago Ramón y Cajal (1852–1934), the father of modern neuroscience — the scientist who first revealed the nervous system as a network of individual cells, drawing by hand the architecture no one else could see.

CAJAL is a foundation model for the autonomic nervous system. It resolves the sympathetic and parasympathetic branches from ordinary heartbeat data — turning a raw trace into a readable picture of the body’s control layer.

The dataset

CAJAL is trained on 25 years of patient clinical data.

How the name earns itself

One nervous system, seen twice — a century apart.

011852–1934
Santiago Ramón y Cajal, photographed circa 1900

The observer

Santiago Ramón y Cajal showed that the nervous system is built from individual cells — the finding modern neuroscience rests on.

02c. 1899
Cajal's ink drawing of astrocytes and neurons in the cerebral cortex

The drawing

No instrument could show that architecture, so he drew it — by hand, from what he saw down a microscope.

A century later
03Today
AI-based spectral separation

The model

CAJAL reads the same system's live signal — resolving the sympathetic and parasympathetic branches from an ordinary heartbeat trace.

Santiago Ramón y Cajal, 1852–1934. Portrait and drawing public domain.
04Access

One signal. Anywhere.

Because it runs on heart rate — one of the most commoditized sensors there is — autonomic measurement no longer needs a specialized clinic. Our mission is to make the body’s most important signal measurable for everyone, on a device they already own.

01 / In-person centers

Specialized centers, dedicated equipment, limited access — waitlists and long consultations.

02 / At home

The same signal, from a simple heart-rate wearable. 12 minutes, at home, anytime.

03 / Anywhere

A simple heart-rate band is enough — wherever you are.

05The science

Two questions: balance, and coherence.

At rest, the autonomic nervous system holds a balance between its two branches — that’s homeostasis. But a balanced system doesn’t just sit still; it responds. When the body is challenged — a deep breath, a change in posture — each branch should react in a coordinated, predictable way. Coherence is whether the body’s physiology responds in step with that expected pattern, or against it. The ANS Test measures both — the resting balance, and how coherently each branch responds across the test’s phases.

Fig. 03 — At rest · balance
Homeostasis = balanced ANS = diagonal
Parasympathetic nervous system →
AAD · DAN
CAN
Normal
Sympathetic nervous system
ANS decline
NormalAAD, DANCAN
Fig. 04 — Under challenge · coherence

The test asks your body to do four things in turn. Each graph follows one side of your nervous system. The shaded band is where it should be in each phase. The line is where it actually went.

Parasympathetic — rest-and-recover side
RestPaced breathingStrain breathingPosture change
Sympathetic — act-and-adapt side
RestPaced breathingStrain breathingPosture change
ParasympatheticSympatheticWhere each side should beWhere it went

At rest, the two sides sit in balance. Under challenge they are not meant to stay balanced — each phase asks one side to lead and the other to step back. Coherence is whether that handover happens cleanly, phase after phase.

Illustrative figure. Not a result, and not intended to diagnose, treat, cure or prevent any disease or condition.

The coherence framework — autonomic resonance and coherence vs. resistance — is drawn from co-founder Dr. Ramesh Adiraju’s published work (J Rheumatol Arthritic Dis, 2017).

General-science figures describing the autonomic nervous system as a field of study. They are not evidence about any Autonomic Health product.

The science →
06Medical pedigree · Our CMO

Built on two decades of autonomic science.

Dr. Ramesh Adiraju, Chief Medical Officer and co-founder
Fig. 04 — Dr. Ramesh Adiraju, CMO & co-founder
Dr. Ramesh AdirajuMD, FACC · Chief Medical Officer & co-founder

Autonomic Health’s science is led by Dr. Ramesh Adiraju, our Chief Medical Officer and co-founder — a physician who has spent more than two decades studying the autonomic nervous system. He founded the Dysautonomia Research Institute (2005, now part of the company) and developed the autonomic coherence framework — resonance and coherence versus resistance — published in the scientific literature (J Rheumatol Arthritic Dis, 2017). His research is the scientific foundation the company is built on.

Dysautonomia Research Institute
HeritageDysautonomia Research Institute · founded 2005 · now part of Autonomic Health
The science →
2005Dysautonomia Research Institute founded — now part of Autonomic Health.
FieldFrequency-domain separation of sympathetic and parasympathetic activity.
Lit.Publications cited in full on the science page.

These citations describe the field and its science — not evidence of product performance.

07The company

AI-native, from day one.

Reading the autonomic nervous system at this scale isn’t possible without AI — it’s why we built the company around a model. The separation above is CAJAL at work: AI-based spectral separation of the two autonomic branches.

Our mission

Make the body’s most important signal measurable for everyone, everywhere.

The team

Engineers, physicians and researchers who came to the same signal from different directions.

Meet the team → About
08The first step

The first step: make it measurable.

Our first product brings autonomic measurement home, for your own wellbeing — the first step in a longer journey to make the body’s control signal part of everyday health.

Our productcloudans.ai ↗

The storefront, pricing, and test experience live on the product site — not here.

The body’s most important signal, finally within reach.

You have carried this signal your whole life. We think you should be able to see it.

We exist to make autonomic measurement available to everyone, everywhere.

Partner with usRead the manifesto